Digestive Health: 7 Ingredients Driving this Booming Market

These days, digestive health is one of the top health concerns for Americans (1) In fact, 86% of people in the U.S. say they regularly experience gastrointestinal issues (2).

Yet, not only is digestive health on the minds of increasing numbers of people, but it is also big a business. In fact, predictions show the sector will grow at 7.2% annually until 2023 (3). Specifically, market experts predict that the global probiotics market will grow to an over $73.0 billion sector by 2024 (4).

Trending Now: Digestive Health

Digestive health products are trending across the food industry, For example, at the end of 2018, the Cincinnati-based Kroger Co. listed gut-healthy foods as “one of its five leading trends heading into the new year.”

In addition, consultancy agency New Nutrition Business named digestive wellness as its top trend for 2019. On top of that, shelf-stable products containing new strains of probiotics have created even more digestive health food options for consumers (5).

Katherine Leaderbrand, consumer health industry analyst, Euromonitor International says that older adults are spending the most money on digestive health products. This is because digestive health issues problems are much more prevalent among older people (6). As increasing numbers of Baby Boomers cross the half-century mark, healthcare spending in on digestive health will only continue increasing.

The Ingredients Behind the Digestive Health Boom

Below are 7 ingredients driving the current boom in digestive health sector:

1. Probiotics

Meaning for life, probiotics are one of the most popular dietary supplements. Although the human gut naturally contains these microorganisms, sometimes, these beneficial bacteria can get out of balance. As a result, taking probiotics helps to restore the balance or helpful bacteria in their gut and aids digestion. What’s more, some people take them for weight loss and to boost their immune system.

As a dietary supplement, probiotics come several forms — powders, tablets, capsules or other forms. Regarding the ingredient, the term ‘probiotics’ refers to the friendly bacteria which manufacturers add to these products. Several varieties of bacteria are used in probiotics. Two of the most common are Lactobacillus and Bifidobacterium. Additionally, some yeasts (like Saccharmyces) have probiotic properties. Depending on the specific additive or product, a dose of probiotics many have between 1 billion or as many as 250 billion of these ‘friendly bacteria’ (7).

2. Prebiotics

Not to be confused with probiotics, prebiotics are “foods (typically high-fiber foods) that act as food for human microflora. Prebiotics are used with the intention of improving the balance of these microorganisms” (8).

In general, dietary prebiotics are nondigestible fibers that aren’t affected by heat, stomach acids, oxygen, and enzymes. They pass through your gut undigested and encourage good bacteria and other microorganisms (microflora) to grow (9). When they arrive in your gut, they help to feed all the friendly bacteria found naturally in your gut (10).

Prebiotics offer several health benefits. Hannah D. Holscher, assistant professor of nutrition at the University of Illinois says that they can help lower inflammation throughout your body, fight off harmful gut bacteria, and boost immunity. She also believes they could positively impact blood cholesterol and triglyceride levels as well as be good for your mental health (11).

3. Synbiotics

Synbiotics combine both probiotics and prebiotics. Not only does the still have all the properties of both, but some people believe the combination is synergistic. This means that the two working together accomplish more good things in your body than if you only took one (1).

4. Abiotics

Abiotics are non-viable (dead) probiotics or cells that can produce health benefits. For example, some people take non-viable probiotics because their bodies handle them more easily than viable (living) probiotics (1).

5. Dietary Fiber

The average American doesn’t get enough dietary fiber. Why is this a problem for digestive health? Because without it, your digestive system doesn’t work as well as it could. Specifically, dietary fiber keeps things moving through your GI tract. Also, the friendly bacteria in your gut feeds on dietary fiber. On top of those things, dietary fiber also fills you up and makes you feel full longer (12). Also, a high-fiber diet can help you control your blood sugar and cholesterol levels (13).

6. Digestive Enzymes

Under normal circumstances, the human body produces enough digestive enzymes naturally in the mouth, stomach, small intestine, gallbladder, and pancreas (14).

However, certain health issues (like irritable bowel syndrome (IBS) and inflammatory bowel disease) may hinder the body’s ability to produce these enzymes. Also, age, stress, inflammation, genetics, and dietary choices can keep your body from producing enough digestive enzymes.

Consequently, some people need extra digestive enzymes. These enzymes include Amylase, Protease, Lipase, Maltase, and others (15). A digestive supplement may contain one or even several of these enzymes.

7. Fermented Foods

In 2017, Whole Foods predicted that fermented foods would become a new trend among its customers (5). These days, it’s common for people in America to consume foods and drinks like kombucha (a fermented sweet tea) and kimchi (a popular Korean condiment made from pickled vegetables). Other popular fermented foods include yogurt, sauerkraut, tempeh (made from fermented soybean), and kefir (a beverage made from fermented milk (16).

Food scientist Robert Hutkins, PhD, of the University of Nebraska-Lincoln says, “If you’re consuming a diet rich in fermented foods, you’re essentially bathing your GI tract in healthy, food-related organisms (16).” Their rise in popularity makes fermented foods one of the top ingredients driving the booming digestive health sector.


It may come as a surprise that the human gut contains trillions of beneficial microorganisms. When these friendly organisms are healthy, then the rest of you is healthy too. In contrast, when your ‘gut flora’, these tiny things living in your gut, are out of balance, the rest of your body suffers too.

Dietary supplements and functional foods with one or more of these ingredients can help you maintain the proper balance of friendly bacteria.




  1. https://khni.kerry.com/news/webinars/webinar-digestive-health-know-your-ingredients/
  2. https://khni.kerry.com/news/blog/digestive-health-part-ii-consumers-take-control/
  3. https://www.marketwatch.com/press-release/digestive-enzymes-market-2019–global-industry-scenario-by-key-companies-future-trend-pipeline-projects-product-application-growth-and-regional-forecasts-to-2023-2019-05-09
  4. https://www.marketwatch.com/press-release/probiotics-market-share-will-exceed-us-730-billion-by-2024-2019-05-03?mod=mw_quote_news
  5. https://www.foodbusinessnews.net/articles/12959-digestive-health-a-top-trend-heading-into-2019
  6. https://www.naturalproductsinsider.com/digestive-health/growth-digestive-health-market-and-popular-ingredients
  7. http://www.berkeleywellness.com/supplements/other-supplements/article/probiotics-pros-and-cons
  8. https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/probiotics/faq-20058065
  9. https://en.wikipedia.org/wiki/Prebiotic_(nutrition)
  10. https://www.bimuno.com/prebiotics/
  11. https://news.yahoo.com/prebiotics-144834014.html
  12. https://www.webmd.com/diet/features/fiber-digestion
  13. https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/fiber/art-20043983
  14. https://www.health.com/digestive-health/digestive-enzymes
  15. https://www.womenshealthnetwork.com/digestivehealth/what-are-digestive-enzymes.aspx
  16. https://www.webmd.com/food-recipes/news/20170213/could-fermented-foods-boost-your-health#1

A Nicotinamide Riboside Supplement May Help Heart Function

As the human body ages, we naturally lose some of our functionality. For many aging people, losing cardiac function is a major concern. In fact, the main risk factor for developing cardiovascular disease (CVD) is age – the older you get, the more likely you are to experience a cardiac event. What’s more, CVD is the number one cause of sickness and death in industrial and post-industrial societies (1).

Although aging a natural part of life, at the same time, there are things we can do to slow the natural aging process and keep our hearts healthy. Recent studies show that taking a nicotinamide riboside supplement may help maintain heart function.

What is Nicotinamide Riboside (NR)?

Like niacin and nicotinamide, nicotinamide riboside (often shortened to NR) is a B3 vitamin. However, certain unique properties set NR apart from those forms of B3 (2). What’s more, in a pre-clinical study, NR proved to be more effective than either niacin or nicotinamide for boosting nicotinamide adenine dinucleotide (NAD+) levels. Also, unlike niacin, NR does not cause flushing (reddening of the skin).

Overall, pre-clinical trials show that NR is superior these standard forms of vitamin B3 (niacin and nicotinamide) (3). Marketed as NIAGEN by ChromaDex Corp., the company states that

Cells can use NR to create nicotinamide adenine dinucleotide (NAD+), which is an essential molecule found in every living cell (4).

Why NAD+ is Important

Clinical trials show that when taken as a supplement, NR can increase NAD+ levels in humans. What’s more, additional ongoing studies continue to investigate NR’s potential (4). Although aging is unavoidable, improving NAD+ levels as people age can potentially do several things to support healthy aging (4). Specifially NAD+ can:

  • Increase cellular metabolism and energy production
  • Help maintain healthy mitochondria
  • Promote cellular repair

Even though scientists have known about NAD+ for over a century, its importance has only recently come to light. Without NAD+ the human body cannot properly generate energy from food. What’s more, research shows that this important molecule may decrease in our body’s as we age. In some cases, metabolic stress can lower NAD+ in your body. In fact, some researchers believe that decreasing NAD+ may lead to declines that we associate with aging (4).

Studies show that NR supplementation definitely raises NAD+ levels. In a 2018 study, 60 healthy middle-aged and older men and women between 55 and 79 years old were given either an oral NR supplement or an oral placebo. In the end, the NR supplement raised NAD+ levels by about 60% when compared to the placebo (1).

NR and Heart Function

Other studies point to NR’s heart-specific benefits. Last month, ChromaDex Corp. reported on a preclinical study done on mice which shows that NR supplementation helps maintain their heart function. NR does this by stimulating ‘the mitochondrial unfolded protein response’ (UPRmt).

This response (UPRmt) is the mechanism that helps mitochondria to function properly. The results of this independent study (led by Principal Investigators Prof. Ajay M. Shah and Dr. Ioannis Smyrnias from Kings College London) have been published in the Journal of the American College of Cardiology (JACC) (5).

Specific to heart function, preliminary studies like the one above show that NR supplementation could help treat a range of age-related cardiac conditions, including heart failure. According to a 2018 research article published in the American Heart Association’s journal Circulation,

Myocardial metabolic impairment is a major feature in chronic heart failure. As the major coenzyme in fuel oxidation and oxidative phosphorylation and a substrate for enzymes signaling energy stress and oxidative stress response, nicotinamide adenine dinucleotide (NAD+) is emerging as a metabolic target in a number of diseases including heart failure (6).

Furthermore, the Circulation article lists some important clinical implications of a diet that includes NR supplementation (6):

  • Could possibly help patients who have experienced heart failure to improve their myocardial ATP supply by improving NAD+ levels.
  • Could also help improve muscle function and metabolic flexibility in individuals who are obese and/or suffer from diabetes mellitus making NR a great option for treating metabolic therapy of heart failure syndrome.

Taking a Nicotinamide Riboside Supplement to Stay Heart Healthy

Staying ‘heart healthy’ as we age has become increasingly important. Because of this, more and more people pay attention to their cardiac health. One way to potentially improve cardiac function and prevent cardiovascular disease (CVD) is by taking a nicotinamide riboside (NR) supplement.





  1. https://www.nature.com/articles/s41467-018-03421-7
  2. https://en.wikipedia.org/wiki/Nicotinamide_riboside
  3. https://www.chromadex.com/wp-content/uploads/2018/11/ProductFactSheet_Niagen_2017_final.pdf
  4. https://www.chromadex.com/ingredient/niagen/
  5. https://finance.yahoo.com/news/study-deepens-research-potential-cardiovascular-103000282.html
  6. https://brenner.lab.uiowa.edu/sites/brenner.lab.uiowa.edu/files/wysiwyg_uploads/diguet18.pdf

Rose Hips Benefits Explained

Rose hips benefits are many. The supplement is widely known for its health benefits.

The rose hip is the round fruit part of the rose plant found below the flower. The fruit is typically red but may also be orange or purple in some variations.

The fruit contains the seeds used to grow the rose plant. In its dried form, manufacturers add rose hip to medicines, supplements and other products.

Since rose hip is rich with several antioxidants, including lycopene and vitamins C and E, it is particularly useful for improving overall health.

Medical professionals believe that rose hip may have a number of health benefits. This article discusses these benefits, which include treating arthritis and improving heart health, in more detail below.

Rose Hips Facts

Rose hips grow where roses are grown. Most commonly, they are found in temperate climates in the Northern Hemisphere, where roses are native.

There are several types of rose species. These variations include rosa gallica (french rose), rosas canina (dog rose) and rosa rugosa (beach rose).

The beach rose is typically found in Asia, while the french rose is native to Europe. In fact, the french rose was one of the first types of roses found in central Europe.

Many types of roses will include rose hips. The beach rose, in particular, includes rose hips. 

Rose hips start to grow in the early summer months. They are most ripe in late August and early autumn.


Many people associate rose hips with their health benefits. However, they have also been used in other forms.

Rose hips are a fruit, and people use them to make jams, jellies, and desserts.

In fact, there is a traditional Hungarian brandy known as “palinka” made using rose hips. The fruit is well known in the country and in its surrounding area, including in Austria.

Many people use rose hips in herbal teas, given their many antioxidants.

Today, rose hip is very popular in supplement form. It is also made as a powder and oil.

Health Benefits

Researchers have identified several rose hips benefits that improve health. These health benefits range from treating the effects of arthritis to fighting obesity and reducing blood sugar levels.

Given these rose hips benefits, it is clear why the supplements are so popular.

Medical research on the effects of rose hip has come to several conclusions about the effectiveness of rose hip.

Here are the key findings on the health benefits of rose hip:


One of the main health benefits of rose hip is alleviating the symptoms of arthritis.

The supplement is able to help prevent the breakdown of joint tissue. It also has an anti-inflammatory effect which helps to manage symptoms.

According to a 2005 study in the Scandinavian Journal of Rheumatology, rose hip can alleviate the symptoms of arthritis. Taking the supplement daily resulted in a reduction of osteoarthritis pain.

After three months of treatment, the rose hip supplement reduced stiffness and overall severity of the arthritis.

In addition, a 2010 study in Phytomedicine concluded that patients with rheumatoid arthritis may benefit from treatment with rose hip powder.

Patients taking rose hip reported improved health and reduced pain following treatment.

There is strong evidence that rosebud can be effective in reducing the pain associated with osteoarthritis, the most common form of arthritis.

Treating Obesity

Believe it or not, rose hip may be a natural treatment for obesity.

A 2015 study found that daily intake of rose hip extract can decrease body weight and abdominal fat area.

According to the study, which studied the effects over a 12-week period, body fat percent “tended to decrease compared with the placebo group.”

Previous studies had shown the anti-obesity effects of rose hip in animals. This recent study established the relationship in humans.

In addition, rose hip can lower cholesterol in the body. The supplement reduces LDL cholesterol, the bad cholesterol that can increase chances of stroke and heart attack.

Immune Strength

Rose hip is a powerful supplement to boost your immune health.

In particular, it is useful because of its high amounts of vitamin C. In fact, rose hip may have more vitamin C than some citrus fruits.

Vitamin C is widely known to improve the immune system. Research shows that vitamin C helps to repair tissue in the immune system. It also prevents more serious complications associated with the common cold.


The benefits of rose hip also extend to diabetes.

For those at risk, rose hip may help lower blood sugar levels and prevent diabetes.

Scientists have shown that rose hip helps reduce high blood pressure and prevent obesity, two conditions associated with type 2 diabetes.

A study in the American Journal of Physiology found that mice had a higher glucose tolerance and lower blood sugar levels after regularly taking rose hip.

This effect may also apply to humans.

In a 2012 study published in the European Journal of Clinical Nutrition, researchers found that 6 weeks of rose hip consumption significantly reduced systolic blood pressure, low density cholesterol and LDL cholesterol.

According to the researchers, rose hip consumption can “significantly reduce cardiovascular risk in obese people through lowering of systolic blood pressure and plasma cholesterol levels.”

rose hips benefits


Rose hip may even have applications in treating cancer.

In fact, one study recently found that rose hip can reduce the growth of cells in breast cancer.

The supplement was particularly useful in responding to a breast cancer called “triple negative.” This is an aggressive cancer that is difficult to fight.

Triple negative is especially prevalent in young women. It most commonly affects African-American and Hispanic women.

The study showed the rose hip extract could “reduce the migration of breast cancer cells by as much as 45 percent.”

Reducing Stretch Marks

In a 2015 study, researchers set out to evaluate the effects of rose hip powder on skin wrinkling and aging.

The study, published in Clinical Interventions in Aging, had an interesting results.

The researchers found that rose hip resulted in “statistically significant improvements in crow’s-feet wrinkles, skin moisture, and elasticity after 8 weeks of treatment.”

Additionally, research found that rose hip oil can help reduce stretch marks in pregnant women.

Women who used the oil twice daily had a lower chance of getting stretch marks than those that did not use the rose hip supplement.

Capsaicin: Hot Peppers and Weight Loss

When you eat spicy food with hot peppers, the burning sensation you feel is caused by something called Capsaicin. Found in plants belonging to the genus Capsicum, notably hot peppers, this compound is an irritant for mammals (1). It’s the reason your mouth burns and your eyes water. And if you wipe your nose or eyes after handling peppers containing capsaicin, you’re sorry afterwards.

However, apart from being a compound which makes foods spicy, capsaicin has other applications too. Due to its properties as an irritant, capsaicin is the main ingredient in pepper spray. Also, it can be used in pest control solutions and is especially effective against mammalian pests and other pests. What’s more, the compound has pain relieving properties. Several analgesic patches and ointments have capsaicin as the active ingredient (1). On top of all, that, capsaicin supplements can help people lose weight.

In this article, we explore capsaicin’s properties as a weight loss aid. Specifically, we’ll examine a few medical studies and also highlight user reviews.

How Does Capsaicin Cause Weight Loss?

How can eating hot peppers cause weight loss? In general, capsaicin gets your heart beating and your blood pumping. Mary-Jon Ludy, an assistant professor of clinical nutrition at Bowling Green State University says, “Because your body perceives that it’s under stress, it burns more calories (2).”

For people who want to lose weight, eating chili peppers or taking a capsaicin dietary supplement can lower your body weight, speed up metabolism, help you burn more fat and even decrease your appetite. Not only that, but consuming capsaicin may also improve physical endurance and athletic performance (3).

Specific Effects

Below are details on capsaicin effects on your body and how it may lead to weight loss (4):

  • Metabolic Rate — Consuming 10g of red pepper with capsaicin seems to increase enhance metabolic rate (the rate at which the body uses energy) for about half an hour after a meal.
  • Fat Oxidation — When the body uses the energy in fatty acids, this is fat oxidation. Taking 150 mg of capsaicin orally an hour before a low-intensity workout has been shown to increase fat oxidation (fat burning) in healthy adult males.
  • Thermogenesis — Capsaicin helps to increase the body’s heat production (thermogenesis).
  • Adipogenesis — There appear to be anti-obese effects of capsaicin supplementation. Specifically, it seems to prevent the adipogenesis — the gathering of triglycerides into fat cells.

Studies on Capsaicin and Weight Loss

Below are some medical studies which highlight the weight loss properties of capsaicin.

Capsaicin and Rabbits

One study used rabbits to examine the effects of capsaicin on body weight. The rabbits were given one of two diets — either a high-fat diet (the control) or high-fat diet with 1% hot pepper. At the end of the study, the rabbits which consumed hot peppers had lower body weights that the other rabbits. The conclusion is that capsaicin can prevent obesity related to diet (5).

Overweight Adults and Capsaicin

In this study, 91 moderately overweight participants were placed on a four-week VLED regime (very-low-energy diet) followed by a three-month weight-maintenance period. Moreover, during this weight maintenance phase, participants were either given a capsaicin supplement or a placebo. In the end, the capsaicin group experienced more fat oxidation than the placebo group (6).

Capsaicin, Mice, and Exercise

Some researchers note a link between exercise, capsaicin, and exercise. In this study, two groups of mice were fed different diets. One group received a normal diet and the other received a high-fat diet along with capsaicin for twenty-five weeks. The group of mice which consumed capsaicin exercised longer and gained less weight. Overall, capsaicin improved endurance and reduced weight gain in the mice (7).

A Review of Several Studies

In a review of several studies, researchers noted capsaicin’s thermogenic properties. Although the compound itself doesn’t contain very much energy, its natural properties cause the body to burn energy. In fact, consuming capsaicin produces a negative energy balance (burns more energy than it contributes). As a result, capsaicin can be useful in anti-obesity therapy. What’s more, it does this without significantly increasing blood pressure. The review of these studies concluded that capsaicin boosts fat burning (8).

Research Summary

According to medical research and the testimonies of real people, taking a capsaicin supplement can help a person lose weight. As a weight loss aid, capsaicin helps your body burn energy, burn fat, and boosts your metabolism. On top of that, it can also improve athletic performance, making your exercise more effective. Furthermore, capsaicin has other health benefits uses as well including anti-inflammatory and pain-relieving properties.

Capsaicin Weight Loss Supplement Reviews

People who have tried capsaicin for weight loss have a variety of reactions. Below are some common things people say about capsaicin supplements:

  • ‘Lose a pound a day’ — One reviewer actually claimed to have lost seven pounds in a single week when they began taking capsaicin for weight loss. Others report losing 10 pounds in two weeks. Although results vary from person to person, many people experience weight loss when taking capsaicin.
  • ‘Won’t make you jittery’ — People who have previously taken other weight loss supplements and appetite suppressants, they comment that taking capsaicin doesn’t make them jittery as the other supplements do.
  • ‘No burn’ — Many people who appreciate the benefits of capsaicin prefer to take a supplement as opposed to eating spicy foods. The main reason is that unlike eating spicy peppers or spicy foods, capsaicin supplements don’t burn their mouths, throat, esophagus, or stomach.
  • ‘Warms me up’ — Other people who take capsaicin for weight loss comment that it warms them up. This is especially helpful for people with slower metabolisms who have a hard time getting warm in winter.

Custom and Stock Formulas From ABH Pharma

Are you looking for a new supplier for your capsaicin supplements? Are you planning to launch your own private label capsaicin supplement? We manufacture both custom formula and stock formula nutraceuticals. To learn more about ABH Pharma, Contact Us today.

  1. https://en.wikipedia.org/wiki/Capsaicin
  2. https://www.realsimple.com/health/nutrition-diet/weight-loss/weight-loss-supplements
  3. https://draxe.com/capsaicin/
  4. https://examine.com/supplements/capsaicin/#ref1
  5. https://www.ncbi.nlm.nih.gov/pubmed/22327653
  6. https://www.ncbi.nlm.nih.gov/pubmed/13129472
  7. https://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=7414018f-3f3d-4983-9074-59d905670698&cKey=260298d9-0e86-472c-b48e-2bd7968621ca&mKey=50056dd1-4b44-4f4a-b685-b88d00f3529b
  8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699483/

How To Make Your Supplement All Organic Using Natural Flow Agents

As you can see illustrated in the diagram to the right, using OrganiFlow™ eliminates the following artificial excipients:

  • Magnesium Stearate
  • Silicon Dioxide
  • Microcrystalline Cellulose
  • Stearic Acid
  • Dicalcium Phosphate

Consumers are trending to be much more aware of nutrition & supplement facts. There is no more need for these potentially harmful artificial ingredients.

What is the Purpose of Excipients?

Excipients have many functions in nutraceutical manufacturing processes. Without them, a supplement cannot be produced. 

Most people don’t realize that ingesting artificial excipients can potentially be harmful to consumers

Excipients are used ubiquitously in the majority of the solid dosage formulations to improve the formulation processability.

Flow agents are used to reducing the interparticle friction, allowing powders to flow through the rotary hoppers. Reducing the die wall friction.

Theme Image

Artificial Excipients allow mixing of various ingredients to be possible

These are considered to be “flow agents”.Flow agents prevent powders from clumping up and sticking together.

Without flow agents, the proportions would not be correct when producing a supplement or vitamin.  

Artificial Excipients act as a filler in capsules

Fillers are mainly used to increase the look appeal of a capsule.

Consumers believe that they are getting a better product if it is full.

Artificial Excipients create a custom color for the formula

Consumers might want a pure white filler or a yellow filler depending on what the supplement is directed to achieve.

Artificial excipients are used to give a supplement a color.

Artificial ExcipientsWant to display this infographic on your site?

Artificial Excipients

Are There Any Substitutes To Artificial Excipients?

Ingredient Evolution has identified this potentially harmful ingredient that millions of people are ingesting in their body every day. We made it a mission goal to remove the need for magnesium stearate and other harmful artificial excipients in the production of supplements and vitamins.

Our team of scientists discovered  a brilliant solution through in-depth research. We have created the first all organic excipient, capable of replacing all artificial excipients.

First, we take a proprietary blend of organic brown rice and grind it into a fine powder. Then through an extensive 3 step conduction oven drying process. We achieved in creating the first all organic excipient. 

Whether or not you believe artificial excipients are harmful to consumers or not, there is no reason to take that risk when there is an all organic excipient replacement.

Realistically if a brand has magnesium stearate, stearic acid, dicalcium phosphate, or silicon dioxide they don’t have any real concern for your health or well-being. They decided to take the cheap route and make their pockets heavier with no consideration how this will affect their customers in any way.

Dried organic brown rice powder is superior to artificial excipients because it performs all necessary functions and has zero side effectsIt can be used as a flow agent which prevents clumping, sticking, and enables the supplement to have a smooth and fast manufacturing process.

What are the Most Common Artificial Excipients?

How Are They Potentially Harmful To Ingest?

Magnesium Stearate / Steric Acid:

Magnesium stearate is synthesized mainly from genetically modified (GMO) plant sources for nutraceutical manufacturing. Coming from:

  • Cottonseed oil – A high-risk genetically modified crop and one of the heaviest residual pesticide sprayed crop.
  • Canola oil – Known as rapeseed oil, also from a high-risk genetically modified crop.
  • Palm oil – Palm oil contains Palmitic Acid, a saturated fatty acid the World Health Organization has identified as a significant contributor to cardiovascular disease.

Poor Absorption Of Nutrients

A major concern of mixing magnesium stearate with vitamins is reduced nutrient absorption. This is especially concerning because consumers purchase supplements & vitamins strictly to absorb those nutrients. A study conducted in 2007 showed that tablets with magnesium stearate dissolved slower than ones without magnesium stearate after being placed in gastric juices. (1)

Suppression Of Immune System

There is evidence that ingesting magnesium stearate weakens your immune system. A study conducted in 1990 shows evidence that T cells absorb the magnesium stearate into their cell membranes before eventually killing the T cells. Your T cells are a primary factor in your immune system. (2)


A study conducted by Japanese scientists in 2009 discovered that magnesium stearate could cause formaldehyde to occur. (3) (4)

Pesticides & Contamination From Manufacturing

A report was done in 2011 by the World Health Organization that batches of magnesium stearate became contaminated with several toxic chemicals. These chemicals included bisphenol A, calcium hydroxide, dibenzoyl methane, Irganox 1010 and zeolite (sodium aluminum silicate) (5)


A study in 2012 reported that a 28-year-old woman had a severe allergic reaction to magnesium stearate. The woman broke out in hives. (6)

Many people also reported on Treato.com that they believe their hives breakout was caused by magnesium stearate. (7)


  1.  (http://bjbms.org/archives/2007-3/uzunovic.pdf)
  2. (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1384169/?tool=pubmed)
  3.  (https://www.jstage.jst.go.jp/article/cpb/57/10/57_10_1096/_pdf)
  4.  (http://www.sciencedirect.com/science/article/pii/0300483X80900268)
  5.  (http://apps.who.int/prequal/info_press/documents/Mg-Stearate_InformationNote_Dec2011.pdf)
  6. (http://europepmc.org/abstract/MED/23241129)
  7.  (https://treato.com/Magnesium+Stearate,Hives/?a=s)
  8.  (http://www.trade-chem.com/products/MSDS/Dicalcium%20Phosphate.pdf)
  9.  (https://www.nlm.nih.gov/medlineplus/druginfo/natural/735.html)
  10.  (http://www.theijoem.com/ijoem/index.php/ijoem/article/viewFile/45/93)

Dicalcium Phosphate:

Skin Irritation

According to Material Safety Data Sheet, skin contact to dicalcium phosphate may lead to a dry or chapped skin. (8)


According to Material Safety Data Sheet, people with allergic reactions to dicalcium phosphate develop dermatitis, an allergic reaction that causes redness, swelling or itching on skin areas that came in direct contact with the irritating substance. In severe cases, the allergic reaction spread to areas of the skin that weren’t in direct contact with the skin. (8)

Negative Inhalation Effects

According to Material Safety Data Sheet, inhalation of dicalcium phosphate powder dust can irritate lungs & nasal passages. Leading to chronic coughing and sneezing. (8)

Negative Gastrointestinal Effects

Evidence gathered from the National Library of Medication & National Institutes of Health showed that high levels could upset the gastrointestinal system. Symptoms include nausea, vomiting, loss of appetite, stomach pain, thirst, dry mouth, and increased urination. (9)

Worsening of Pre-Existing Conditions

Evidence gathered from the National Library of Medication & National Institutes of Health showed ingestion of dicalcium phosphate can increase the severity of people with problems like diarrhea, parathyroid disease, lung disease, kidney stones, & other stomach related problems. People who have any of these problems should consult a physician before taking a supplement with dicalcium phosphate. (9)

Silicon Dioxide:

The U.S. Environmental Protection Agency placed silicon dioxide in Toxicity Category III

Causes Silicosis

Silicosis is a lung disease caused by inhaling tiny bits of silica over a period of time.

Increased Risk of Chronic Kidney Disease

A 2012 study published in the journal Renal Failure found a connection between silica exposure and chronic kidney disease. (10)

OrganiFlow is the Leading Organic Excipient!

OrganiFlow is the alternative to artificial excipients. It is an all-organic excipient, which is a simple brown rice powder that substitutes and outperforms artificial excipients.

OrganiFlow is a patent pending breakthrough in the nutraceutical industry created by Ingredient Evolution.

Not only does this product make your supplement artificial excipient free, it also improves water distribution, texture, and consistency. This is a product that will improve capsules appearance and fullness with no harmful side effects to the consumer.

This mitigates risk on the supplier and also creates a more healthy, attractive, and efficient appeal to the company.

Key Benefits of OrganiFlow

Organiflow is the alternative to artificial excipients. These excipients can be harmful and have negative side effects. Using OrganiFlow will:

  • Mitigate risk of negative side effects
  • Increase efficiency of your product
  • Improves texture, capsule appearance, water distribution, and uniformity
  • Improves company image
  • Separates your company with this exclusive product

Why is OrganiFlow the Future to Organic Excipients?

OrganiFlow is an organic excipient that has the same functions as the artificial excipients.

Companies that will use this product will have the most effective product on the market. This will create appeal to their product which will attract demand as well.

OrganiFlow is a revolutionary product to help further advance companies and keep the consumer with a healthy and clean supplement. Our objective is to keep the nutraceutical industry healthy and give our clients a leg up on their competition.

Companies are forced to use flow agents in the production of capsules to keep the machines running correctly and having the correct proportion of ingredients.

Therefore, what Ingredient Evolution has accomplished is, replacing all artificial excipients such as magnesium stearate, stearic acid, dicalcium phosphate, silicon dioxide and other harmful excipients with an all-natural organic flow agent.


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The End Result

In essence, what Ingredient Evolution has accomplished is, replacing all artificial excipients with an organic excipient. This will allow you to state your product as an Artificial Excipient Free (AEF). What we strive to achieve is client satisfaction and more importantly client growth.