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CRN’s New Campaign Highlights FDA’s Supplement Label Changes

In the near future, consumers of dietary supplements will see changes to labels on their favorite vitamins, minerals, protein powders, and extracts. In order to help consumers understand these changes, CRN (The Council for Responsible Nutrition) launched a Be Label Wise campaign (www.BeLabelWise.org). CRN’s campaign explains the new FDA label guidelines and offers several resources for consumers and industry insiders.

The site has a two-minute video which reviews the Supplement Facts label and introduces the changes. What’s more, the site also has other helpful educational tools like an Infographic, a section entitled ‘How to Read a Supplement Facts Label’, a Fact Sheet, and Tips for Consumers (1). Consumers and industry insiders can access the entire toolkit at https://belabelwise.org/stakeholder-toolkit/.

The Time for Change

As a leader in the supplement industry, CRN applauds the FDA’s upcoming label changes. Brian Wommack, senior vice president, communications, CRN says:

The ‘Supplement Facts’ label had not been updated for many years and it was time for the labels to reflect the current science and nutrient needs of Americans. With the support of its members and a creative outside agency, CRN has developed a campaign that accomplishes many goals, in particular, communicating that Supplement Facts labels are changing to better provide consumers the information they need to make informed choices about their health (2).

Wommack also addresses the need to ease consumers’ minds about the label changes. CRN wants consumers to value the helpfulness of updated labels. As a result, CRN launched this educational campaign. Moreover, the organization hopes industry leaders and key stakeholders will share and spread the Be Label Wise campaign.

Also, even though anyone can use the educational content in stakeholder toolkit, the tools can also be customized and branded. CRN also has social media tools with graphics with text to help the campaign reach even more people.

Additionally, Wommack states that 75% of Americans take dietary supplements. He then sees these upcoming changes as a great opportunity for the nutritional supplement industry to educate consumers.

Specific FDA Supplement Facts Label Changes

According to the new FDA’s new labeling guidelines, below are specific changes consumers will see on the new labels (3):

  • New Daily Values (DVs) — will be based on changes in the American diet and updated nutrition science
  • Vitamin A, D, and E amounts — will change from International Units (IU) to milligrams (mg) and micrograms (mcg)
  • Folic acid — will now be listed as folate and measured in mcg of dietary folate equivalents or DFEs
  • Added sugar — Updated labels will contain amount and % DV of added sugar

The FDA’s changes will go into effect in 2020 and 2021. Manufacturers who have over $10 million in annual sales must comply by January 1, 2020. For manufacturers with less than $10 million in annual sales, they have until by January 1, 2021, to comply with the new guidelines (4).

At the same time, the Be Label Wise campaign points out that the compliance date is based on when the product is actually labeled, not according to shipping or shelving dates. Furthermore, some companies may even change their labels well in advance of the deadlines.

FDA Supplement Facts Labels History and the Need for Changes

After passing the Dietary Supplement Health and Education Act of 1994 (DSHEA), the FDA’s Supplement Facts became a part of federal regulations in 1997. The FDA amended these guidelines the following year and once again in 2003.

Located on dietary supplements, the FDA created the Supplement Facts label to inform consumers about the nutrient make-up of nutritional products. According to FDA regulations, each label must list the ingredients, serving size, % Daily Value (DV), the product’s suggested use, and other important information that consumers should know.

Since the previous updates happened over a decade and a half ago, the FDA decided to make changes. Two major factors led to these changes to Supplement Facts labels. Firstly, the average American diet has changed in the past few decades. Secondly, there have been many advances in nutrition science. Facing these two things, the FDA now asks supplement companies to update their labels based on the new guidelines.

About CRN

Since 1973, this Washington, D.C.-based trade association has been the leading trade association for the dietary supplement industry. CRN represents over 150 companies in the industry, from suppliers to manufacturers. CRN expects all members to follow all relevant federal and state regulations regarding quality control, manufacturing, marketing, and safety. Furthermore, CRN members must also to adhere to voluntary guidelines and CRN’s Code of Ethics.

 

 

 

References

  1. https://belabelwise.org/
  2. https://www.crnusa.org/newsroom/crn-launches-campaign-educate-consumers-dietary-supplement-label-changes
  3. https://belabelwise.org/fact-sheet/
  4. https://www.fda.gov/food/food-labeling-nutrition/changes-nutrition-facts-label
by Will Cartwright Will Cartwright No Comments

Everything To Know About Vegetable Capsules Explained

Vegetable capsules provide a convenient alternative for those who cannot eat meat or meat products. They offer all the benefits of a typical capsule without the issues associated with dietary restrictions.

Capsules are two-piece enclosures that are typically made from gelatin. The capsule contains active ingredients for medications or supplements.

Compared to tablets, capsules have several advantages. First, people can easily swallow them. Capsules also break down more quickly in the digestive system.

If you can’t swallow a tablet, consider trying a capsule. You can easily open them and empty their contents into food or beverages.

Vegetable capsules are similar to gelatin capsules with a few main differences related to their composition.

Overview of Vegetable Capsules

Today, there are many people that choose to eliminate meat from their diets.

The reasons for doing so range from environmental concerns to religious considerations and health issues.

According to a recent Gallup poll, there are millions of Americans that are vegans or vegetarians. Younger people are more likely to vegetarian than people over 50.

In fact, sales of plant-based food products increased by 8.1% in 2017. Total sales were more than $3.1 billion.

These facts demonstrate the need for plant-based alternatives to the typical capsule.

What They’re Made of

Vegetarian capsules are typically made of vegetable cellulose.

There are several different types of vegetable cellulose that make up vegetable capsules.

One of these materials is hypromellose. This type of cellulose comes from softwood trees, such as pine, spruce and fir trees.

In particular, such trees are grown in the Northern Hemisphere in temperate climates. However, they can grow in both cold and warm environments with sufficient water and quality soil.

Manufacturers use hypromellose in many commercial products. It functions as a popular alternative to animal gelatin. In addition to its use in vegetable capsules, it functions as a binder or coating in tablets.

Because of its composition, hypromellose is a suitable substance for capsules. It can delay the release of active ingredient into the digestive tract.

Advantages of Vegetable Capsules

Vegetable capsules are the perfect vegetarian alternative to regular capsules.

They provide all of the quality that comes from the gelatin tablet without the animal products.

Vegetable capsules are also tasteless. It’s hard to tell the difference between a vegetarian and a gelatin capsule.

Anyone who cannot eat gelatin made from animal products because of environmental, health or dietary restrictions should consider vegetable capsules.

Like gelatin capsules, vegetable capsules are perfect for digestion and can slowly release the active ingredients in a capsule as need. In addition, many people use vegetable capsules in both powdered and gel forms. There are no clear limitations in terms of usage.

The capsules are generally Kosher and Halal certified. Therefore, those with religious dietary restrictions prefer them.

The capsules come in many different sizes and colors.

Gelatin Capsules Compared

When it comes to capsules, gelatin is the most common type.

This is how manufacturers originally made capsules and how they have generally made them over time.

Gelatin comes from cows and pigs. To make it, you boil the hooves, skin and bones of the animal to create a gel-like material.

This process releases a collagen from the animal tissue. After boiling, the substance cools. Gelatin goes through a significant amount of processing. Therefore, it is not officially an animal product, according to some people.

However, many strict vegetarians will avoid gelatin because it originates from animals.

Advantages of Gelatin Capsules

There are several clear advantages related to gelatin capsules.

First, they are very inexpensive. You can easily purchase large quantities of these capsules at a relatively low price.

vegetable capsules

Vegetable capsules tend to be more expensive because the materials are more costly.

The capsules also come in a variety of colors and sizes. Gelatin is easy to make and shape into different forms. It is also odorless.

Gelatin itself has several health benefits, including improving skin health and digestive functions and easing joint pain.

Hard-Shelled vs. Soft-Shelled Capsules

There are two types of capsules to note. The first is known as a “hard-shelled” capsule. This type of capsule contains a dry or powdered active ingredient.

The hard-shelled capsule is composed of two halves. The “body” contains the active ingredient, and the “cap” seals the top. An automated manufacturing process allows to take place seamlessly.

With hard-shelled capsules, you can remove the cap and empty the contents of the capsule into food or beverages.

The other type of capsule is the “soft-shelled” capsule.

This is a single-piece capsule that can include liquid active ingredients. Some people might also refer to soft-shelled capsules as liquid gels.

Soft-shelled capsules are good for increasing the permeability of the drug. The drug more evenly distributes through the body.

Both hard-shelled and soft-shelled capsules are made of gelatin.

Similarities between Vegetable and Gelatin Capsules

There are clear differences between gelatin and vegetable capsules in terms of how they are made.

However, there are still some similarities between these two types of capsules.

You may also consider both types of capsules in comparison to tablets. Many people prefer capsules over tablets because they are easy to swallow.

Capsules keep for a significant amount of time without going bad. Both gelatin and vegetarian capsules store easily for long periods of time.

In addition, both of these capsules are odorless and even tasteless. There is no need to worry about medication or supplements with an unpleasant taste or smell.

Finally, both vegetable and gelatin capsules dissolve easily in the digestive system. They are much easier to swallow than tablets.

Given these similarities and differences, it’s important for each person to consider which type of capsule is better for them.

Choosing Between Capsules

Vegetable capsules are great for vegetarians, but they might not be suitable for everyone.

Gelatin capsules offer the same benefits and are available at a lower price.

Generally, if you don’t have a problem eating animal products, there is no reason to avoid gelatin capsules.

They offer great quality and can be easily absorbed by your digestive system.

by Will Cartwright Will Cartwright No Comments

How GMP Manufacturing Benefits Your Business

Good manufacturing practice, or GMP manufacturing, is a way to make sure that products meet high standards for quality and control.

GMP manufacturing covers all aspects of the manufacturing process. It includes everything from the ingredients and equipment used to the training of personnel.

The idea behind GMP manufacturing is to eliminate risks at every stage of the production process. This way, manufacturers aren’t just relying on the testing of the final product to ensure that it meets the highest safety and quality standards.

GMP is sometimes also called cGMP. The “c” here stands for current. It’s a reminder that good practices are often changing, and technologies and equipment are evolving all the time.

Given that consumers value high-quality products, GMP manufacturing is popular both from a production standpoint and a marketing perspective.

Procedures & Qualifications

In the United States, the regulations for GMP manufacturing are enforced by the U.S. Food and Drug Administration (FDA).

Typically, regulators will provide general guidance for GMP manufacturing. Then, manufacturers will have to decide how to implement the guidelines.

The guidelines for GMP manufacturing may include general guidance such as the following:

  • The workplace must be clean, safe and sanitary.
  • The manufacturer must investigate complaints about products.
  • Processes must be clearly defined and controlled.
  • The facility must keep proper records about manufacturing processes.
  • The manufacturer must have a system in place to recall products.
  • The manufacturer must implement quality control mechanism.

As you can see, these guidelines do not tell manufacturers exactly what they have to do. Instead, they provide general guidance about issues related to quality, safety and controls.

This flexibility allows manufacturers to set quality controls that work for their business.

At the same time, GMP manufacturing guidelines help to set standards across industry.

GMP manufacturing guidelines cover manufacturing, testing, quality control, personnel, safety and more. They may include issues related to records, staff qualifications, equipment specifications, complaints, and quality control mechanisms.

Enforcing GMP Regulations

Clearly, GMP manufacturing regulations aren’t effective, if they aren’t enforced.

Since the guidelines are sometimes vague, enforcement is especially important to ensure proper application and use.

For this reason, regulators will conduct inspections on manufacturing facilities to evaluate manufacturers for compliance.

In the United States, for example, the FDA regularly conducts inspections of facilities. They inspect both the sources of active ingredients and the facilities in which they are manufactured into finished products.

These inspections are effective because the regulators are well trained in the areas of safety, quality and process controls.

Regulators will also pay close attention to consumers’ reports about unsafe or low quality products. This information helps to guide the regulators’ decisions about inspections and potential risk.

Importance of GMP Manufacturing

In truth, it can be difficult to tell if a product is safe or up to standards.

For supplements especially, product safety and quality is hard to discern from the smell or taste of the product.

That’s why it’s important that mechanisms are in place to ensure the product is safe when it’s in the hands of the consumer.

Testing is not the only answer to ensuring safety and quality. These principles must integrated throughout the manufacturing process.

The fact is that testing only covers a small percentage of the total product produced by the manufacturer. It’s a sample.

By implementing these guidelines, the manufacturer ensures that each step of the process is up to standard.

In doing so, the manufacturer increases the likelihood that the product is both high quality and safe.

For example, if procedures are in place to regularly test the active ingredients that go into supplements, then the manufacturer can catch potential problems before the product is even made.

Benefits of GMP Manufacturing

In terms of safety, the benefits of GMP manufacturing are clear. Even one defective or unsafe product is too many.

A product recall can cost a business millions of dollars in damages and lost profit. In addition, it affects the company’s brand.

Stories about unsafe or defective products make consumers less likely to trust your business and less likely to buy your product.

GMP manufacturing makes sense from both a cost perspective and a marketing perspective.

The investment in high-quality equipment and thorough internal procedures is important, and it will pay off in the long run.

Compliance issues or a product recall can cause more damage to your business than what it takes to invest in GMP manufacturing measures.

Using the GMP Manufacturing Label

GMP manufacturing labels help communicate quality to the consumer.

When they see a label that says “Manufactured in a GMP Facility,” they’ll know that the product is safe and that the manufacturer produced it with high standards.

The label improves the perspective of consumers and retailers. Retailers want products in their stores that are safe and trusted. Ultimately, they want their products to sell.

When you use the GMP Facility label, you elevate your product over the competitors.

GMP manufacturing

In many cases, supplement manufacturers will follow GMP manufacturing guidelines, but they won’t advertise it on the label. This is a missed opportunity.

It’s always a good idea to reinforce the quality and safety controls that are behind your product.

Consumers might not know exactly what went into manufacturing the finished product, but they will appreciate that you prioritized testing, quality control, and safety.

Conclusion

GMP manufacturing facilities meet high standards for safety and quality at every stage of the manufacturing process.

From ingredient sourcing to equipment maintenance and personnel training, these facilities have mechanisms in place to ensure high standards.

GMP manufacturing processes can be an investment. They take time and money to put into place, but they pay off for a business.

GMP manufacturing is great for business because consumers value quality and safety. Consumers can trust that GMP manufacturing facilities have produced a quality product.

That’s why manufacturers shouldn’t be afraid to tell the consumer how they made the product.

Using a “Manufactured in a GMP Facility” label is an effective way to communicate to the consumer that your business values safety and cares about quality products.  

by Will Cartwright Will Cartwright No Comments

Types of Nutraceutical Companies in the Nutraceutical Industry

The nutraceutical market is a growing industry. One of the main reasons for this growth is consumers’ greater awareness of their own health, especially as they age. On top of that, many people with chronic health issues and diseases turn to more natural methods instead of pharmaceutical solutions.

Also, due to poor nutrition in some places, there is an increasing emphasis on food fortification by governments. Overall, there is a great demand for these products. As a result, increasing demand for nutraceutical ingredients causes the price of raw materials to also rise (1).

What are Nutraceuticals?

Nutraceuticals (a combination of the words ‘nutrition’ and ‘pharmaceutical’), are standardized nutrients which the FDA regulates as dietary supplements and food additives (2). There are several types of nutraceuticals:

  • Dietary supplements — Vitamins, minerals, amino acids, herbs, and enzymes marketed in various forms: tablets, capsules, gelcaps, softgels, powders, and liquids. Some popular dietary supplements include vitamin D, calcium, ginseng, and fish oil (3).
  • Functional foods — Fortified or enriched foods that are marketed beneficial to consumers’ health (2).
  • Medical foods — Prescribed by physicians and taken under medical supervision. Often given to surgical patients and premature babies (4).
  • Farmaceuticals (‘farm’ and ‘pharmaceutical’) — Made from genetically-engineered crops or animals to provide more nutrients (4).

The Supply Chain

Raw Material Farmers & Producers

The best nutraceuticals begin with the best raw materials. However, not all raw materials have the same quality. When considering raw materials, farming practices, pesticide use, purity, uniformity, and traceability of ingredients are all concerns (5). As a result, the first step in quality control is starting with superior raw materials.

Raw Material Wholesalers

In order to get the raw materials they need, every manufacturer works with supply partners. These wholesale partners source the raw materials from the farmers and producers, then sell them to manufacturers. The nutraceutical ingredients market can be divided into ingredients based on (6):

  • Type — vitamins, minerals, prebiotics, probiotics, proteins & amino acids, omega-3 fatty acids, specialty carbohydrates, plant extracts, etc.
  • Application — dietary supplements, functional food, functional beverages, and personal care
    Form — dry and liquid
  • Health benefits – heart health, gut health, bone health, weight management, etc.

As stated above, superior nutraceuticals begin with great raw materials. So finding a wholesale partner (or partners) to supply raw materials is vital to manufacturing the best products.

Contract Nutraceutical Manufacturing Companies

ABH Pharma is a supplement manufacturer that produces supplements from custom formulas. At the same time, clients can opt for our stock products. What’s more, we offer additional options like bottling and boxing custom products. Our entire process, from procuring raw materials to production to labeling and packing is based on FDA guidelines and follows the strictest standards of quality control (7).

Nutraceutical Manufacturing Brokers

Unlike manufacturers, nutraceutical brokers are simply middlemen. Even though they advertise themselves as manufacturers, they outsource production to third-party manufacturers. In reality, they only have storage/distribution and/or packaging certifications.

Since they don’t have manufacturing certifications, these brokers don’t oversee the manufacturing process. Thus they can’t verify their products’ quality and consistency. In general, get your contract and then raise the price on the manufacturer’s quote. Avoid these brokers at all cost

Sample label and bottle.

Labeling, Packaging, and Marketing

One of the most crucial elements for successful nutraceuticals is branding. When you develop a recognizable brand along with a high-quality product, customers associate quality with the brand. As a turnkey manufacturer, ABH Pharma helps you develop and establish your brand through custom labeling, packaging, and marketing.

Packaging Design and Printing

Your products’ packaging design directly influences consumers. For example, custom design and packaging can boost sales by improving marketability and differentiating your products.
ABH Pharma is a full-service nutraceutical manufacturer, but we also create attractive packaging. In fact, we are also an industry leader in label design, FDA label compliance, supplement packing design, and printing. What’s more, we also design and print inserts.

Packaging Options

Once you settle on a product and a label design, package design is next. Ideally, a nutraceutical company should offer a wide variety of packaging options. ABH Pharma offers top quality packaging materials like bottles, jars, and packaging for various doses. On top of that, we also offer display boxes, folding cartons, shrink-wrapped containers, blister packs, and other packaging options.

Marketing

In addition to being a nutraceuticals manufacturer, ABH Pharma is also a contract supplement marketing firm. We work with brands to help them expand their reach and be more competitive, both in physical stores and online.

Fulfillment Warehouses and Shipping Nutraceutical Products

Regardless of where you plan to sell your products (online, in a brick and mortar store, as an Amazon fulfiller, or all three), ABH Pharma offers comprehensive fulfillment services for nutraceutical companies:

  • We warehouse your products and track your inventory using our state of the art 3PL software.
  • Moreover, we send you alerts and reports of your inventory and shipments which you may check anytime via our online web portal.
  • Additionally, we help with shipping logistics. Since we have good relationships with shipping companies, we’re able to negotiate shipping rates to benefit our clients.

Vitamin Brands Selling Vitamins to Regular Consumers Through Smart Marketing

These days, it possible to build a thriving supplement and vitamin-selling business by selling directly to consumers. Social media and online stores have opened an entirely new world for sales. By marketing themselves and their products, a supplement seller can build a base of regular customers and carve out a niche market for themselves.

Choose ABH Pharma

If you want to develop your own private nutraceutical label or add new products to your existing nutraceutical line, ABH Pharma is the smart choice. Contact Us today to learn more about ABH Pharma’s services and products for nutraceutical companies.

References:

  1. https://www.marketwatch.com/press-release/top-companies-of-nutraceutical-ingredients-market-industry-are-basf-se-archer-daniels-midland-company-associated-british-foods-plc-dsm-ingredion-arla-foods-amba-2019-04-12
  2. https://en.wikipedia.org/wiki/Nutraceutical
  3. https://www.fda.gov/Food/DietarySupplements/UsingDietarySupplements/ucm109760.htm
  4. https://www.wisegeek.com/what-are-the-different-types-of-nutraceutical-products.htm
  5. https://www.sciencedirect.com/science/article/pii/B008045044X000146
  6. https://www.marketwatch.com/press-release/top-companies-of-nutraceutical-ingredients-market-industry-are-basf-se-archer-daniels-midland-company-associated-british-foods-plc-dsm-ingredion-arla-foods-amba-2019-04-12
  7. https://blog.abhpharma.com/supplement-packaging-design-how-product-boxes-could-boost-sales
by Will Cartwright Will Cartwright No Comments

Manufacturing Pharmaceutical Grade Supplements

Whenever consumers purchase nutritional supplements, product quality might never cross their mind. Yet in recent years, several major retailers have been caught selling low-quality or fraudulent supplements. A few years ago, Wal-Mart, Target, GNC, Walgreens were confirmed to be selling fake herbal supplements (1). These products were falsely labeled, falsely advertised, and contaminated with undisclosed additives.

According to New York State’s Attorney General, only 21% percent of the store brand supplements sampled contained any of the herbs listed on the labels. Below are some specific examples (2):

  • A Walgreens store brand of ginseng pills only contained powdered garlic and rice.
  • Ginkgo biloba sold at Walmart contained powdered radish, bits of houseplants, and wheat (contrary to the label’s claim of being both wheat-free and gluten-free).
  • 3 out of 6 herbal products sold by Target (St John’s wort, ginkgo biloba, and valerian root) contained none of these herbs. They did contain ingredients like powdered rice, beans, peas, and wild carrots.

What does it mean to be a pharmaceutical grade supplement manufacturer?

Customers should never worry whether supplements contain the ingredients listed on the label. They shouldn’t be concerned whether they might ingest impure, harmful ingredients. Unlike other purveyors of supplements, ABH Pharma always adheres to the highest production and quality control standards. Beginning with pharmaceutical-grade ingredients, we manufacture the highest-quality supplements.

What is ‘Pharmaceutical-Grade’

‘Pharmaceutical-grade’ means that the ingredients meet pharmaceutical standards. Specifically, pharmaceutical grade vitamins and supplements must be exceedingly pure without binders, fillers, dyes, or unknown substances. In contrast, ‘food grade’ ingredients are fit for human consumption. To distinguish pharmaceutical grade, below are the four categories of nutritional supplements (3):

  • Pharmaceutical grade – The highest quality grade for ingredients. They meet the highest regulatory standards for purity, dissolution, and absorption.
  • Medical grade – Also high-grade, but not as high as pharmaceutical grade standards.
  • Cosmetic or nutritional grade supplements – Unlike Pharmaceutical or Medical grade supplements, these might not be thoroughly tested. What’s more, this grade of supplements may not have the same concentrations of active ingredients as the label claims.
  • Feed (agricultural) grade – Intended for veterinary use

Being a Pharmaceutical Grade Manufacturer?

Dietary supplements are increasingly popular among people who want non-pharmaceutical solutions for health needs. In fact, by 2025, the supplement industry is expected to grow into an $11.4 billion industry (4).

Sadly, manufacturers of various quality have entered the supplement market. Hoping to cash in on the popularity of nutraceuticals and other dietary supplements, some unscrupulous companies don’t follow strict standards. Not only that, but their facilities can’t produce pharmaceutical grade supplements.

In comparison, ABH Pharma is passionate about delivering only the best stock formulas and custom supplements. Specifically, our in-house facilities consist of quality control departments, encapsulators, tablet presses, powder mixers, several bottling lines, packaging tools, and more.

ABH Pharma Adheres to the Highest Standards

In contrast to some other manufacturers, ABH Pharma follows a strict Quality Insurance Process when manufacturing nutrition-based supplements. Consequently, we can deliver some of the most accurately produced supplements in the industry. From sourcing to shipping, ABH Pharma’s entire process happens in-house. As a result, we can guarantee the quality of all materials, formulas, and finished products.

Firstly, we begin with the best raw materials. Next, our pharmaceutical grade ingredients pass our strict quality control process. After that, we send the ingredients to our pharmacy compound for testing, verification, weighing, and blending. Therefore, we can guarantee that every label claim is accurate.

Over the years, ABH Pharma has received FDA, NPA, and GMP certifications. Consequently, we follow all regulatory guidelines when manufacturing pharmaceutical grade supplements. Moreover, because we do all formula assessments and ingredient testing in-house, nothing leaves our facility until it is packaged and ready to ship. In summary, we refuse to manufacture products that do not meet regulations, claims, or our high standards.

ABH Pharma is Pharmaceutical Grade!

ABH Pharma’s mission is providing superior nutraceuticals and excellent service throughout our entire process. Not only that, but we offer a full range of solutions including Custom Formulas, Stock Formulas Packaging, Label Design & Compliance, Fulfillment, and Testing.

We manufacture tablets, capsules, softgels, and even gummy vitamins in our in-house facility for any brand, size, or type of business. What’s more, we also handle labeling and packing to get your products ready for shipping.

From our quality control team to your sales rep, each person on our team delivers superior service. In fact, we equip each member of our staff with extensive knowledge of supplement and vitamin development. Contact us today and let us tackle your supplement, health product, or vitamin.

References

  1.  https://www.salon.com/2015/02/03/walmart_target_walgreens_gnc_accused_of_selling_scam_herbal_supplements/
  2. https://www.smh.com.au/lifestyle/health-and-wellness/the-supplements-scandal-herbal-pills-do-not-always-contain-ingredients-on-label-20150205-1376ec.html
  3. https://health.howstuffworks.com/wellness/food-nutrition/vitamin-supplements/determining-supplement-quality.htm
  4. https://markets.businessinsider.com/news/stocks/global-sports-nutrition-and-supplements-market-to-2025-11-4-bn-growth-opportunities-investment-opportunities-1004145947
by Will Cartwright Will Cartwright No Comments

What is Magnesium Stearate?

Magnesium stearate can be derived from animal and plant sources. At room temperature, this substance takes the form of a white powder (1). This powder is “greasy to the touch. Practically insoluble in water and in ethanol (2).” The chemical formula is: Mg(C18H35O2)2. In the past, the supplement industry used magnesium stearate due to its lubricating properties.

Producing this artificial substance involves a reaction between sodium stearate and magnesium salts. Another production method involves treating magnesium oxide with stearic acid. Some nutritional labels tell whether the sodium stearate in the manufacturing process is vegetable-derived stearic acid or not (3).

Specific Uses

Magnesium Stearate is an excipient. According to Merriam-Webster, an excipient is usually an “inert substance that forms a vehicle (as for a drug) (4).” Also known as ‘flow agents’, manufacturing supplements and other products is almost impossible without excipients. Recognized as safe by the FDA, magnesium stearate is valued for its lubrication properties. Specifically, excipients like magnesium stearate keep powders from clumping and sticking together. They also prevent ingredients from sticking to manufacturing equipment (5).

Since magnesium stearate is safe in low doses, soft, and mostly insoluble, it is favored as an excipient (flow agent) by certain industries. The pharmaceutical, cosmetic, nutritional supplement, and nutraceutical industries commonly use magnesium stearate. Companies use this FDA-approved inactive ingredient to manufacture capsules, tablets, and powders.

Many supplements and vitamin formulas contain complex formulas and multiple ingredients with various chemical properties. Because of this, the ingredients can tend to stick together. As a result, manufacturers add excipients to prevent sticking and caking. On top of that, excipients also help to ensure consistency and maintain the correct proportions of supplements and vitamins. If a manufacturer cannot achieve consistency, then the product cannot meet the label claims (6).

Magnesium Stearate as a Flow Agent

As stated above, magnesium stearate is a flow agent used in vitamin manufacturing. Using it prevents ingredients from caking and adhering to the equipment. As a result, it makes the manufacturing process easier and more cost-effective.

Magnesium Stearate Alternatives

To manufacture supplements properly, ABH Pharma must use flow agents. As stated above these substances allow our machines to run efficiently, so we can effectively produce a wide range of products. Due to their crucial importance to the nutraceutical industry, excipients are unavoidable.

However, negative effects may accompany artificial excipients. Although they are deemed safe in small doses by the FDA, artificial excipients also can be harmful beyond certain doses. As a result, there are alternatives to excipients like magnesium stearate.

At the same time, we can choose the types of flow agents we use. Since one of our main goals objective is keeping the nutraceutical industry healthy, we choose to use organic excipients. Below are two specific types of organic excipients along with their benefits.

OrganiFlow

One of the leading organic excipients is OrganiFlow (7). Made from brown rice powder, this alternative to artificial excipients is totally organic. Furthermore, this patent-pending flow agent represents a breakthrough for the nutraceutical industry. This revolutionary product provides consumers with healthy, clean supplements and also gives our clients an advantage over their competition.

Created by Ingredient Evolution, OrganiFlow keeps supplements free from artificial excipients. With OrganiFlow, Ingredient Evolution has created all-natural, organic alternatives to artificial excipients like magnesium stearate. In the manufacturing process, it “improves water distribution, texture, and consistency.”

On top of that, it also improves capsules appearance. What’s more, as a harmless filler, it helps to fill capsules without harmful side effects. Moreover, using OrganiFlow creates healthier, more attractive products, appealing products.

OrganiFlow Benefits

Below are the major benefits of using OrganiFlow for supplement manufacturing:

  • Reduces the risk of negative side effects which come from artificial excipients
  • Improves your product by enhancing capsule appearance, texture, water distribution, and uniformity.
  • Makes your product more efficient
  • Sets your company apart from the competition
  • Boosts your company’s image

Nu Flow

Another option for replacing artificial flow agents in the manufacturing process is patent-pending Nu-FLOW. Created by RIBUS, this excipient is created from sterilized, ground rice hulls. RIBUS is a leading worldwide producer of rice-based alternatives to artificial excipients. In addition, the company is also a leader in the ‘clean label movement (8).’

These rice husks contain a lot of natural silica which can be made into a powder. This fine powder functions like magnesium stearate and other artificial flow agents. Yet it does not have any of the same ill effects. Nu-FLOW comes in two varieties – Organic Nu-FLOW and Natural Nu-FLOW (9).

Nu Flow Benefits

Some specific benefits of Nu-FLOW are:

  • Acts as an effective flow agent and improves processing
  • Allows your products to achieve over 95% organic levels
  • Replaces synthetics with ‘rice concentrate’ allowing for ‘clean label’ statements

Organic Excipients: The Future of Flow Agents

Consumers are becoming more conscious of what they put into their bodies, and rightly so. With this rising demand for healthy, organic ingredients, supplement suppliers must keep pace with consumer trends. Overall, organic excipients represent the future of the nutraceutical industry.

Excipients like OrganiFlow and Nu-Flow provide the same functionality as artificial excipients, but without the health concerns. What’s more, companies like ABH Pharma which use organic excipients to manufacture supplements give your products an advantage in the marketplace.

The appeal of organic, non-artificial ingredients allows you to meet the need of consumers as well as attract new demand for your products. Consequently, replacing artificial excipients with organic excipients lets you label your product as an Artificial Excipient Free (AEF).

Learn More About ABH Pharma

ABH Pharma is a turnkey contract supplement manufacturer. We specialize in producing tablets, capsules, powders, and softgels. We are known across the industry for our unrivaled commitment to product quality and our exceptional turnaround times. ABH Pharma is ready to produce natural, organic nutraceuticals for your company. To learn more about our manufacturing process, Contact Us today.
References:

  1. https://www.drugs.com/inactive/magnesium-stearate-147.html
  2. https://www.sciencedirect.com/topics/medicine-and-dentistry/magnesium-stearate
  3. https://en.wikipedia.org/wiki/Magnesium_stearate
  4. https://www.merriam-webster.com/dictionary/excipient
  5. https://www.drugs.com/inactive/magnesium-stearate-147.html
  6. https://www.livestrong.com/article/37138-side-effects-magnesium-stearate-/
  7. https://abhpharma.com/make-supplement-organic-using-natural-flow-agents/
  8. https://www.ribus.com/abh-pharma-ribus-ccm-program/
  9. https://www.ribus.com/nu-flow/
by Will Cartwright Will Cartwright No Comments

Choosing the Right Supplement Contract Manufacturer

supplement contract manufacturerWondering if you should work with a supplement contract manufacturer? We’ll outline the benefits to your business and your bottom line.

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The supplement industry is huge right now. How huge? $30 billion-a-year-huge. And experts agree the industry is poised to grow further.

Right now, natural wellness and preventative health solutions are popular among both baby boomers and younger generations. Thanks to new research on alternative health care, along with new technology developments, consumers are able to take their health into their own hands and focus on natural preventative measures.

There are also different health trends happening right now. For instance, much attention has been given to certain natural supplements that stimulate focus and increase mental cognition. And the benefits of ketones continues to populate many print and digital news and marketing channels.

If you’re thinking of getting into the supplements space, now is a great time to grab your share of the ever-growing revenue. And if you need some help getting your product line off the ground, you should consider working with a supplement contract manufacturer (SCM).

What Does a Supplement Contract Manufacturer Do?

Supplement contract manufacturers are different from regular manufacturers because they go above and beyond just manufacturing your products. SCMs take care of the entire process of making and shipping the products you sell. This means from creation to fulfillment, they handle each and every step on your company’s behalf, so you can continue to focus on growing your business and profit margins.

Benefits of Working with a Supplement Contract Manufacturer

Let’s take a closer look at how working with a SCM can benefit you:

Better Efficiency Means Higher Revenue

One of the biggest culprits of higher manufacturing costs and lost time is a lack of efficient processes. Supplement contract manufacturers put efficiency first in order to completely streamline the entire process.

As an example, a supplement contract manufacturer can source raw materials locally so there is no need for excess shipping costs. This not only moves the process forward faster and cuts costs, but it also reduces environmental impact by reducing shipping distances. This “green manufacturing” is something a supplement company can use in their marketing.

More Enticing Packaging

Let’s be honest – packing plays a very large role in a customer’s buying decision. In fact, a recent study revealed that 7 out of 10 consumers admit that packaging design influences their buying choices.

SCMs have their fingers on the pulse of what is currently working in the supplement space. They can oversee the entire packaging process from beginning to end, creating and executing designs that will stand out on the shelves.

Predictable Timelines

Consumers expect to order something online and have it shipped to them immediately. If there is any sort of delay, they will cancel their order and take their business elsewhere. When your manufacturing process is spread out over multiple companies, there is always a chance the process will become bogged down.

But, by working with a SCM, every step of the manufacturing is connected to the same company, and timeline management is far simpler and easy to control. This means no unexpected delays or keeping customers waiting.

supplement contract manufacturerScalability

Because SCMs work with numerous customers, they have the processes, equipment, and manpower in place to be able to scale. This means you can grow your business and your revenue exponentially.

How to Choose the Right Supplement Contract Manufacturer for Your Supplement Business

Now that you know some of the benefits a SCM can offer your business, let’s look at some ways you can determine which manufacturer to work with:

Do Their Manufacturing Certifications Meet Your Needs?

To begin narrowing down your options, you’ll want to determine which manufacturers have the certifications that meet your needs. To do this, think about what your final product specifications will be, then create a list of requirements for your potential SCM partner. For instance, will you need your product to be 100% organic or kosher? If so, your partner will need the proper certifications.

Do They Offer Formulation?

Unless you have a large enough budget to hire a chemist who will formulate the perfect balance of ingredients, you’ll need a SCM with a high level of experience in this department. The best SCM will have a chemist on staff that can work with you to design supplements that offer optimal benefits to consumers. This not only saves you money but guarantees your product actually works.

Can They Help You with EVERY Step Along the Way?

Remember, you’re not shopping around for just a manufacturer, you’re selecting a true partner who will take care of all of the logistical steps of creating, packaging, storing and shipping your product.

You’ll want a definite track record from the SCM you are considering. Ask if you can speak with some of their other customers to get an idea of what it is like working with them. Take your time on this step, as you want to be absolutely certain the company you choose can handle your business for you with no interruptions or hiccups.

Do They Have the Capability to Produce Your Product and Future Line Extensions?

Starting a business means thinking of the future. Can the company help you grow your product line? Will they be able to offer different dosage formulas and perhaps even more convenient packaging like stick packets?

What are Their Lead Times?

What is the time frame, on average, from purchase order to product release? A word of caution: you may assume you should go with the SCM that offers the shortest lead times. But be aware that very quick lead times could be a sign that the company potentially cuts corners.

Why Work with ABH Pharma?

We understand there are a lot of supplement contract manufacturers out there you could choose to work with. So why work with us?

We take our job very seriously and believe your products should contain what they say, do what they claim, and be safe for consumption. We’ve been in this business a while and know how to design supplements and their packaging for maximum success.

We also offer incredible customer service so you can feel confident and secure.

If you have any questions at all about what we do and how we can benefit you, please don’t hesitate to get in touch with us.

by Will Cartwright Will Cartwright No Comments

What is Pharmaceutical Grade Manufacturing for Supplements?

pharmaceutical grade

Wondering if your supplements should be pharmaceutical grade? The short answer is yes. But keep reading to find out exactly why.

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The US supplement industry made roughly $30 billion last year, and experts predict that number will climb to $32 billion in 2019. With numbers like these, it’s no surprise that more companies are coming into the space with the hopes of getting their share of that revenue. But making a profit in the nutraceutical industry is not as easy as it used to be.

In recent years, the industry has come under scrutiny because of numerous stories about trusted brand name supplements that were found to not meet manufacturing standards or best practices. In 2015, the New York state attorney general’s office accused four national retailers of selling dietary supplements that were fraudulent in their claims. In some cases, the supplements were contaminated with unlisted ingredients.

These revelations caused many consumers and physicians to become leery of supplements. It’s one thing to waste money on a product that will not do what it has promised. It’s another thing to have that same product be harmful to your health.

Pharmaceutical Grade Manufacturing VS cGMPs

You may not realize it, but currently, dietary supplements are not regulated by the Food & Drug Administration (FDA) in the same way that prescription and over-the-counter medications are. Medications are manufactured under much tighter regulations.

The term “pharmaceutical grade” refers to the manufacturing processes used to produce these medications. All medications must go through a rigorous approval process before they ever get to market. The FDA also makes sure that every new drug is put through a series of clinical trials to test its safety and efficacy. Only when the drug meets the FDA’s standards of approval is it made available to the public.

But pharmaceutical grade manufacturing goes beyond just meeting the FDA’s approval. A drug company must also possess a unique monograph. This is similar to how a food manufacturer might have a unique industrial recipe. A monograph describes the exact, step-by-step procedure for making the drug, including exact specifications for sourcing raw materials. This ensures that the safety and efficacy of the drug is consistently maintained.

cGMPs Don’t Stack Up

The supplement industry is currently not held to the same standards as the pharmaceutical industry when it comes to its manufacturing processes. Instead, dietary supplements and other nutraceuticals are subject to their own unique set of cGMPs (current good manufacturing practices) that have been established by the FDA.

While the FDA has actively enforced these cGMPs and cracked down on those who have been found in non-compliance, this usually occurred after supplements had hit the market and a complaint was lodged against the company.

This has been the system in place for supplement manufacturing since the 1990s. But in a recent statement, FDA commissioner Scott Gottlieb, M.D., announced that the organization wants to consider imposing tighter regulations.

“We are announcing a new plan for policy advancements with the goal of implementing one of the most significant modernizations of dietary supplement regulation and oversight in more than 25 years,” he said. “We know that most players in this industry act responsibly. But there are opportunities for bad actors to exploit the halo created by quality work of legitimate manufacturers to instead distribute and sell dangerous products that put consumers at risk.”

What will these new regulations require from supplement manufacturers? No one is certain. But it’s safe to say that from here on, supplement companies would be wise to follow pharmaceutical grade manufacturing procedures.

Benefits of Pharmaceutical Grade Manufacturing for Supplements

pharmaceutical gradeBesides the obvious benefit of being recognized as trustworthy and responsible by the FDA, there are some other benefits to implementing pharmaceutical grade manufacturing processes in your own company. These have to do with your company’s perception among doctors and consumers, and perception is key when you want to be #1.

More Bioavailable

In order for a supplement to be effect, it must first be absorbed by the body. Consumers know this and are actively looking for supplements that have proven they are very bioavailable.

Supplement manufacturers that adhere to pharmaceutical grade manufacturing processes create products that are far more bioavailable than many of their competitors. This is because the FDA requires that medications must be absorbed into your body at a maximum of 45 minutes.

Pure

For a supplement to be pharmaceutical grade, the raw ingredients must be tested prior to production. This testing process is what finds and removes any contaminants that may be present in the sourced ingredients.

Pharmaceutical grade supplements may also not contain any binders, fillers, dyes, excipients or other unknown substances. This is one of the biggest concerns of consumers of supplements. They do not want to think they are taking something that supports their health, only to find the supplement contains something that is harming them.

By following strict pharmaceutical grade manufacturing procedures in your company, you ensure your product is 99% pure without additives or unnecessary substances which may cause unwanted side effects for your customers.

Exact Dosage

Pharmaceutical Grade supplements require that the dosage in each individual supplement is identical to what the label says is in the product. Many current supplements on the market that don’t follow these strict guidelines are offering approximate dosages.

Final Takeaway

Today’s consumers are savvy, and they don’t part with their money easily. Most will research numerous supplement companies, or get a recommendation from their doctor, before making a purchasing decision.

To be a trusted name in today’s marketplace, supplement brands must partner with a reputable manufacturer that follows the strictest pharmaceutical grade manufacturing processes. This ensures your supplements are bioavailable, pure, and dosed accurately.

At ABH Pharma, we take nutraceutical manufacturing very seriously and provide a pharmaceutical grade product you can market confidently. Our team can tackle your health product, supplement, or vitamin. From softgels to gummy vitamins, we will take care of developing, manufacturing and getting your product ready to be shipped and put on shelves.

We also provide superior customer service and are more than happy to answer any questions you may have.

Get in touch with us today.

by Will Cartwright Will Cartwright No Comments

Manufacturing Diet-Specific Supplements

Amy was born with Type I Diabetes. To manage her diabetes, she learned what to eat and what not to eat throughout her childhood. By middle school, she routinely gave herself insulin injections.

Yet in her young adult years, her diabetes symptoms became harder to manage, even with the proper diet. Specifically, as she got older, Amy experienced nerve pain in her hands and feet, a common issue for diabetics.

Although family and friends told her that prescription pain medications would ease her pain, Amy was reluctant to take them. She’d heard the horror stories of people abusing pain pills and wanted to stay away from them. After consulting with her physician, she learned that dietary supplements could help with her nerve pain. So on the advice of her doctor, Amy tried a number of supplements to deal with the symptoms of diabetes.

ABH Pharma Manufacture Supplements for Specific Diets

People like Amy who deal with chronic or acute health issues have learned that taking dietary supplements can be beneficial for their health and well-being. Consequently, manufacturing supplements for specific diets is extremely helpful to support people with specific health needs. Below are some benefits of diet-specific supplements.

Benefits of Diet-Specific Dietary Supplements

Apart from general dietary supplements, like fish oil or vitamin D, there are health conditions which require certain nutrients. If a person who’s dealing with these issues eats follows a certain diet, it then helps them to deal with symptoms of their condition. On top of that, dietary supplements can be an advantageous addition to a person’s diet. Below are some of these health issues along with recommended diets and supplements for each. Before choosing a dietary supplement for a specific health condition, consult your doctor.

Rheumatoid Arthritis and an Anti-Inflammatory Diet

Rheumatoid Arthritis (RA) is a chronic inflammatory disorder. To clarify, this autoimmune disease causes the immune system to attacks the joints. In addition to joint inflammation and pain, people with RA may also deal with fatigue, decreased appetite, and a low-grade fevers. In some cases, it may also affect the body’s systems as well as the organs (1).

The Arthritis Foundation offers some dietary guidelines for people dealing with rheumatoid arthritis. In general, people with arthritis should choose a well-balanced diet centered on plant-based foods. Two-thirds of this diet should be made up of fruits, vegetables and whole grains.

At the same time, the rest of the diet should consist of low-fat dairy products and lean sources of protein. On top of that, eating cold-water fish, like salmon and trout as well as extra-virgin olive oil may help reduce arthritic inflammation. In addition to the above dietary recommendations, people with arthritis may benefit from the following supplements:

  • Selenium – contains antioxidants which some people believe help to control inflammation
  • Vitamin D – helps to regulate the immune system
  • Fish Oil – omega-3 fatty acids have strong anti-inflammatory properties (2)
  • Capsaicin – has pain-relieving properties
  • Tumeric (Curcumin) – reduces joint pain and swelling (3)

Supplements in a Diabetic Diet

Diabetes is a metabolic condition which inhibits the body’s ability to process sugars properly. A diabetic’s lack of insulin means that eating too much sugar could be life-threatening. Consequently, the American Diabetes Association recommends certain foods for diabetics. These include plenty of fruits and vegetables and foods with lean protein. What’s more, the ADA advises diabetics to eat less added sugar and no trans fat (4).

Furthermore, the following dietary supplements can be beneficial for diabetics:

  • Omega-3 Fatty Acids – help to keep the heart healthy; reduce inflammation
  • Vitamin D – offers many benefits for overall health including strengthening bones
  • Alpha-Lipoic Acid (ALA) – may help with diabetes-related nerve damage
  • Magnesium – may be helpful for diabetics with low levels of magnesium (5)

Supplements for a Fibromyalgia Diet

There is no specific recommended fibromyalgia diet. In general, people who suffer from fibromyalgia should eat as healthy as possible. In addition to following a healthy diet, people with fibromyalgia can also benefit from dietary supplements. Below are a few of these supplements which could play a role in better health when living with fibromyalgia:

  • Vitamin C – assists with proper cell growth; also has antioxidant properties
  • Vitamin E – maintains a healthy level of red blood cells, helps develop muscles, and strengthens the immune system
  • Calcium – promotes restful sleep and muscle relaxation
  • Zinc – helps reduce muscle twitching and weakness, promotes relaxation, and reduced anxiety (6)

An MS Diet and Supplements

Briefly stated, MS (multiple sclerosis) is a chronic disorder. Although some people propose an ‘MS diet’, there are no set guidelines. Overall, a person with MS should maintain good health by eating a planned, well-balanced diet. According to the National Multiple Sclerosis Society:

In general, MS specialists recommend that people with MS adhere to the same low-fat, high-fiber diet recommendations of the American Heart Association and the American Cancer Society for the general population. In addition, the MS Society highlights the following dietary supplements for people with MS:

  • Vitamin D – promotes calcium absorption to strengthen bones; is known as an immune system booster; may also help regulate cell growth and differentiation
  • Biotin – considered a form of vitamin B, it helps break down certain substances in the body (7)

How Diet-Specific Supplements Are Made

At ABH Pharma, we know that supplements are extremely helpful to support specific diets. Like Amy, the diabetic at the beginning of this article, increasing numbers of people choose supplements over drugs.

We also see that the dietary supplements have become increasingly popular among people searching for non-pharmaceutical solutions. In fact, the supplement industry is predicted to grow to an $11.4 billion industry by 2025 (8). Some people take diet-specific supplements to improve their overall health. On the other hand, others take certain supplements to address specific health needs.

ABH Pharma produces diet-specific supplements of all types. We have received FDA, NPA, and GMP certifications and adheres to the strictest standards. Regardless of which diet-specific supplement you need produced, ABH Pharma provides stock formulas as well as custom formulas. Not only do we use only the best raw materials, but the entire process, from sourcing to production, happens in-house. Specifically, we follow a strict Quality Assurance Process:

  • All ingredients pass through stringent quality control (testing and verification)
  • Our pharmacy compound weighs and blends ingredients
  • Production and packing happens at our facility
  • We even design custom labels for customized packaging

Since we set such high standards for formulating and producing all of our diet-specific supplements, we guarantee the materials, formulas, and finished products.

Let ABH Pharma Make Your Supplements

ABHPharma manufactures a full range of supplements for any size business or brand. Contact us today and learn how we can produce your diet-specific supplements`.
References

  1. https://www.arthritis.org/about-arthritis/types/rheumatoid-arthritis/
  2. https://www.arthritis.org/living-with-arthritis/arthritis-diet/anti-inflammatory/rheumatoid-arthritis-diet.php
  3. https://www.arthritis.org/living-with-arthritis/treatments/natural/supplements-herbs/9-supplements-arthritis.php
  4. http://www.diabetes.org/food-and-fitness/food/what-can-i-eat/making-healthy-food-choices/
  5. https://www.rd.com/health/conditions/diabetic-diet-supplements/
  6. https://www.fibromyalgia-symptoms.org/care/supplements.html
  7. https://www.nationalmssociety.org/Living-Well-With-MS/Diet-Exercise-Healthy-Behaviors/Diet-Nutrition
  8. https://markets.businessinsider.com/news/stocks/global-sports-nutrition-and-supplements-market-to-2025-11-4-bn-growth-opportunities-investment-opportunities-1004145947
by Will Cartwright Will Cartwright No Comments

Understanding Tablet Manufacturing

Today, tablet manufacturing is on the rise. Companies are more likely to manufacture a supplement as a tablet than any other dosage form. In fact, almost one-half of all drugs are tablets.

Scientists define tablets by their solid form. They typically consist of active pharmaceutical ingredients and excipients. Manufacturers use these substances to bulk up and stabilize the mixture.

Tablets come in all different shapes, sizes and weights. Their size and shape depend on their intended use and method of manufacture.

Often, we classify tablets by how they are made, either as compressed tablets or molded tablets.

Tablet Manufacturing Process

The goal of manufacturing is to create tablets that are chemically stable, uniform in size and shape, and capable of dealing with the shocks associated with production and delivery.

Creating tablets that are uniform in both form and substance requires a process that ensures consistency.

Tablet manufacturing is a complicated process that includes multiple stages of production.

This process transforms the active ingredients into a new substance. The substance delivers the correct dosage at the proper time.

There are three main methods of manufacturing: wet granulation, dry granulation, and direct compression.

Wet Granulation

This is one of the most common methods for tablet manufacturing. This method uses a liquid to agglomerate the dry powder.

Often, the liquid is used in combination with a binder or binding agent. This ensures that the mixture remains strong. Binders may include natural gums or gelatin.

These substances must be carefully controlled and measured. Technicians ensure that the tablet does not turn out to be too soft or too fragile.

The process for manufacturing tablets by the wet granulation method is as follows:

  1. Ingredients and bulking agents are carefully weighed and measured.
  2. Technicians add the liquid binder to the powder.
  3. A screen forms pellets out of the mixture.
  4. The granulation dries in a dryer.
  5. The granules mix together with other substances, such as lubricants.
  6. The granules pass through another screen. It compresses each tablet into a uniform size and shape.

Dry Granulation

This is a process for manufacturing tablets without using a liquid binder. Instead of using moisture and heat to bind the mixture, this method uses compaction to create the granules.

Although less popular than wet granulation, dry granulation may be used when the substance is sensitive to liquid or heat.

The process begins with the compression of powder particles into compacts. This is typically completed by a tablet press or rotary press.

A screen then processes the compacts and breaks them down into granules. This method is typically conducted in one of two ways: using slugging tooling or on a roller compactor.

This method has fewer steps than wet granulation. It also requires less equipment. It is a particularly useful method for substances that are sensitive to moisture and heat.

Dry granulation is simpler and less costly. However, it is not necessarily the preferred method of manufacturing tablets. In recent years, the popularity of this method has decreased. On the other hand, direct compression is more widely used.

Direct Compression

This method avoids the need for granulation in the manufacturing process.

Unlike the wet and dry granulation methods, this method only includes powder mixing and compression. Fewer processing steps means that direct compression is both more efficient and less costly.

At ABH Pharma, tablet manufacturing has an average 4-week delivery time because our manufacturing is in-house.

Since this method is a simple process, there are fewer differences in each batch. There is also greater stability across the batch.

It does not require heat or moisture. It can also be used with sensitive agents.

These benefits make this method the most widely used for manufacturing today.

Types of Tablets

Tablets come in all different shapes, sizes and weights.

However, most tablets are round or capsule shaped. This allows patients to easily swallow them. The size of the tablet often depends on its intended use.

The tablet must be hard enough to stay together in its packaging. It must also be soft enough to dissolve during digestion.

Tablets include both pills and caplets. Pills are small, round, solid dosage forms. Caplets are smooth, capsule-shaped tablets.

Many consumers view capsules as a more efficient way of swallowing a tablet. Today, companies design tablets in many different shapes and colors. This helps distinguish the medication from other brands.

Benefits of Tablets

Tablet manufacturing offers many clear benefits. The most significant benefit is the ability to mass produce at a low cost. In terms of production and distribution, tablets provide an easy and safe way to package and ship.

Many companies pack tablets in “blister packs,” which allow users to view the tablets without opening the packaging.

Doctors and patients often prefer tablets. This is because they’re light in weight and easy to handle. Unlike other dosage forms, tablets offer a high degree of stability and allow for greater accuracy in measuring dosages.

In addition, tablets can be customized with color coatings and other markings. These designs allow users to easily identify the tablet and distinguish it from other medications.

For pharmaceutical companies and manufacturers, it provides them with the opportunity to imprint their brand image onto the product itself.

Drawbacks of Tablets

Despite these benefits, there are several drawbacks to consider. First, it may be hard for some people, especially children and the elderly, to swallow tablets.

Additionally, some evidence suggests that there may be variation in the way different patients absorb tablets. This absorption depends on the digestive system’s ability to process active ingredients.

tablet manufacturing

It’s important to realize that some drugs simply are not suitable for the tablet dosage form. In particular, drugs that dissolve slowly or have large dosages may be difficult to manufacture as a tablet.

Insulin, for example, must be injected into the body. Since it is composed of proteins, the digestive system would not handle it properly if taken by mouth. Therefore, it cannot be taken orally.

Custom Tablet Manufacturing

Tablet manufacturing is fast and cost-effective. It allows for a high degree of customization. It also maintains the stability of the substance. At ABH Pharma, we manufacture tablets using premium press and coating machines.

Our tools create custom tablets that are high quality and that give consumers a high degree of choice in designing their tablets.